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Volume 24 , Issue 5
September/October 2004
Pages 476–487

Comparative Study of Enamel Matrix Derivative with or without GTR in the Treatment of Class II Furcation Lesions in Dogs

Plínio Regazzini, Fo, DDS/Arthur B. Novaes, Jr, DDS, PhD/Paulo T. de Oliveira, DDS, PhD/Daniela B. Palioto, DDS, PhD/Mário Taba, Jr, DDS, PhD/Sergio L. S. de Souza, DDS, PhD/Márcio F. M. Grisi, DDS, PhD

PMID: 15506029
DOI: 10.11607/prd.00.0600

Chronic Class II furcation lesions were created in four dogs. After 21 days, group 1 remained as a control, group 2 was treated with membranes and enamel matrix derivative (EMD), and group 3 received EMD alone. Healing in group 1 was characterized by a long junctional epithelium and discrete bone formation; group 2 showed reduced bone formation; and group 3 showed significant bone regeneration (area of new bone = 67.36% ± 3.93%; distance from furcation roof to bone crest = 0.57 ± 0.15 mm). The EMD led to significant regeneration of the furcation lesions, and the association with membranes was detrimental. (Int J Periodontics Restorative Dent 2004;24:476–487.)

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